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Acetaminophen side effects

Aggregated from 4 medical sources. Not medical advice. Always consult a healthcare professional.

79 side effects

Side effectFrequencyMedlinePlusDrugs.comWalk-In Urgent CareGoodRx
Nauseavery commonnauseanausea or vomitingNauseaNausea
HeadachecommonheadacheheadacheHeadache
RashrarerashrashRash or allergic reactionSevere skin reactions
Liver damagerareliver damageliver failureLiver damage
DeathraredeathDeath
Autism Spectrum Disorder (ASD)Autism Spectrum Disorder (ASD)
Attention Hyperactivity Deficit Disorder (ADHD)Attention Hyperactivity Deficit Disorder (ADHD)
Rednessredness
Swellingswellingswelling, pain, or tenderness in the upper abdomen or stomach area
Vomitingvomitingnausea or vomiting
Hiveshiveshives
Itchingitchingpruritus
Hoarsenesshoarseness
Difficulty breathing or swallowingdifficulty breathing or swallowing
Yellowing of the skin or eyesyellowing of the skin or eyesyellow eyes or skin
Upper belly painupper belly painstomach cramps or pain
Dark urinedark urine
Pale stoolspale stools
Loss of appetiteloss of appetiteloss of appetite
Sweatingsweatingincreased sweating
Extreme tirednessextreme tirednessunusual tiredness or weakness
Flu-like symptomsflu-like symptoms
Unusual bleedingunusual bleedingunusual bleeding or bruising
Bruisingbruisingunusual bleeding or bruising
Bloody or black, tarry stoolsbloody or black, tarry stools
Bloody or cloudy urinebloody or cloudy urine
Feverfever with or without chills (not present before treatment and not caused by the condition being treated)
Back painpain in the lower back and/or side (severe and/or sharp)
Pinpoint red spots on the skinpinpoint red spots on the skin
Sore throatsore throat (not present before treatment and not caused by the condition being treated)
Mouth soressores, ulcers, or white spots on the lips or in the mouth
Decreased urine outputsudden decrease in the amount of urine
Anaphylaxisanaphylaxis
Hypersensitivity reactionshypersensitivity reactions
Increased hepatic transaminasesincreased hepatic transaminases
Liver failureliver failure
Dry mouthdry mouth
Anemiaanemia
Postoperative hemorrhagepostoperative hemorrhage
Thrombocytopeniathrombocytopenia
Leucopenialeucopenia
Neutropenianeutropenia
Prurituspruritus
Serious skin reactionsrareserious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysisSevere skin reactions
Pemphigoid reactionpemphigoid reaction
Pustular rashpustular rash
Lyell syndromeLyell syndrome
Dyspneadyspnea
Abnormal breath soundsabnormal breath sounds
Pulmonary edemapulmonary edema
Hypoxiahypoxia
Pleural effusionpleural effusion
Stridorstridor
Wheezingwheezing
Coughingcoughing
Peripheral edemaperipheral edema
Hypertensionhypertension
Hypotensionhypotension
Tachycardiatachycardia
Chest painchest pain
Hypokalemiahypokalemia
Hyperglycemiahyperglycemia
Dizzinessdizziness
Dystoniadystonia
Muscle spasmsmuscle spasms
Trismustrismus
InsomniauncommoninsomniainsomniaInsomnia
Anxietyanxiety
Oliguriaoliguria
Infusion site paininfusion site pain
Injection site reactionsinjection site reactions
Periorbital edemaperiorbital edema
Pyrexiapyrexia
Fatiguefatigue
Malaisemalaise
Kidney failurerareKidney failure
ComarareComa
Upset stomachcommonUpset stomach
Allergic reactionrareRash or allergic reaction

9 additional sourcesdidn't return structured side-effect data: FDA, Mayo Clinic, WebMD, RxList, Cleveland Clinic, Ubie, Always Best Care, Medical News Today, Consumer Notice.

Demographic risk groups

GroupRiskSources
pregnant womenCategory C – animal studies show riskMedlinePlus, GoodRx
people with liver diseaseliver damageMedlinePlus
people who drink three or more alcoholic drinks every dayliver damageMedlinePlus
childrenoverdose riskMedlinePlus
children 2 through 11 years of ageserious side effectsMedlinePlus
breast-feeding womenunknownMedlinePlus
Elderly (>65)Higher risk of liver damageWalk-In Urgent Care
Heavy alcohol usersIncreased risk of liver damageWalk-In Urgent Care
People taking excessive amounts of acetaminophenHigher risk of liver damage, kidney failure, coma, and deathGoodRx
People with pre-existing liver diseaseHigher risk of liver damageGoodRx

Medside aggregates publicly available side-effect information for reference only. It is not medical advice. Always consult a healthcare professional before making decisions about medication.

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