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Alendronate side effects

Aggregated from 5 medical sources. Not medical advice. Always consult a healthcare professional.

80 side effects

Side effectFrequencyMedlinePlusMayo ClinicBonehealthandosteoporosis.orgMedsafe.govt.nzSynapse.patsnap.com
Abdominal paincommonstomach painAbdominal paingastric ulcerAbdominal painabdominal pain
AllergyAllergy
AngioedemaAngioedema
ArthralgiacommonJoint painArthralgia
Atypical femoral fracturesrareatypical femoral fracturesatypical femoral fractures
Black stoolsblack, tarry, or bloody stools
Blisteringblisters or peeling skinBlistering, peeling, or loosening of the skin
Bloatingcommonbloating or fullness in the stomachBloating or swelling
Bone paincommonsevere bone, muscle, or joint painBone, joint, or muscle painbone painmusculoskeletal pain
BronchospasmBronchospasm
Carpal tunnel syndromerareCarpal tunnel syndrome
Chest painuncommonchest painChest painchest painchest pain
ChillsuncommonChillsflu-like symptoms
ConfusionConfusion
ConstipationcommonconstipationConstipationDiarrhoeaconstipation
CoughCough
DiarrheacommondiarrheaDiarrheaDiarrhoeadiarrhea
Difficulty breathingraredifficulty breathingDifficulty with breathingtrouble breathing
Difficulty swallowingcommondifficulty swallowingDifficulty with swallowingdifficulty swallowingdifficulty swallowing
DiscomfortDiscomfort
DizzinesscommondizzinessDizzinessdizziness
DyspepsiacommonDyspepsia
EpiscleritisrareEpiscleritis
Esophageal irritationuncommonIrritation or pain of the esophagusesophageal irritation
EsophagitisuncommonOesophagitisesophagitis
Eye painrareeye painRed, irritated eyesuveitisOcular pain
FeveruncommonfeverfeverFever
Fullnesscommonbloating or fullness in the stomachFull or bloated feeling
Gastric ulcercommongastric ulcerGastric ulcerationulcers
Gastrointestinal hemorrhageGastrointestinal haemorrhage
Gum infectionrarepainful or swollen gumsgum infection
Hair lossHair loss
HeadachecommonheadacheHeadacheheadache
HeartburncommonheartburnHeartburnheartburnheartburn
HiveshivesHives or weltsUrticaria
Hoarsenesshoarseness
Hypocalcemiahypocalcemia
Irregular heartbeatsIrregular heartbeats
ItchingrareitchingItchingPruritisitching
Jaw painrarenumbness or heavy feeling in the jawHeavy jaw feelingjaw pain
Joint paincommonswelling of the joints, hands, or legsJoint painmuscle, joint, or bone pain
Laryngeal edemaLaryngeal oedema
Loosening of teethloosening of the teethLoosening of a tooth
MalaiseMalaise
Muscle crampscommonmuscle spasms, twitches, or crampsMuscle crampsmuscle spasms
Muscle paincommonsevere bone, muscle, or joint painMuscle painmusculoskeletal pain
Muscle spasms
MyalgiacommonMyalgia
NauseacommonnauseaNauseanauseanausea
Numbnessrarenumbness or heavy feeling in the jawNumbness and tinglingnumbness
Ocular painOcular pain
Oesophageal strictureOesophageal stricture
Oesophageal ulcerationOesophageal ulceration
Osteonecrosis of the jawrareosteonecrosis of the jawosteonecrosis of the jawOsteonecrosis of the jawosteonecrosis of the jaw (ONJ)
PharyngitisPharyngitis
PhotophobiaPhotophobia
Photosensitivity rashPhotosensitivity rashes
PolyarthritisrarePolyarthritis
PruritisPruritis
RashrarerashSkin rashRashesrash
Red skin lesionsRed skin lesionsRed skin lesions
RednessRedness
SeizuresSeizures
ScleritisrareScleritis
Sensation of spinningSensation of spinning
Skin peelingblisters or peeling skinBlistering, peeling, or loosening of the skin
Sore throatSore throatPharyngitis
Stevens-Johnson syndromerareStevens Johnson syndrome
StomatitisStomatitis
Swellingcommonswelling of the joints, hands, or legsSwollen jointsswelling
SynovitisrareSynovitis
TearingTearing
Thigh painraredull, aching pain in the hips, groin, or thighsthigh or groin pain
TinglingNumbness and tinglingtingling
Toxic epidermal necrolysisrareToxic epidermal necrolysis
Trouble breathingraredifficulty breathingTrouble breathingtrouble breathing
UrticariaUrticaria
UveitisrareuveitisUveitis
VomitingcommonVomitingVomiting
Vision changeVision changeAbnormal vision

4 additional sourcesdidn't return structured side-effect data: Accessdata.fda.gov, My.clevelandclinic.org, GoodRx, Perks.optum.com.

Demographic risk groups

GroupRiskSources
pregnantalendronate may remain in your body for years after you stop taking itMedlinePlus
breast-feedingalendronate may remain in your body for years after you stop taking itMedlinePlus
people who have osteoporosisincreased risk of breaking the thigh bone(s)MedlinePlus
childrenaccidental ingestionMedlinePlus
people with severe kidney diseasehigher riskBonehealthandosteoporosis.org
people with low blood calciumhigher riskBonehealthandosteoporosis.org
people with certain problems of the esophagushigher riskBonehealthandosteoporosis.org
patients with poor kidney function or kidney failurehigher riskBonehealthandosteoporosis.org
postmenopausal womenosteoporosisMedsafe.govt.nz
menosteoporosisMedsafe.govt.nz
patients with previous upper gastrointestinal pathologyincreased risk of gastrointestinal adverse effectsMedsafe.govt.nz
patients taking NSAIDsincreased risk of gastrointestinal adverse effectsMedsafe.govt.nz
Oncology patientsHigher risk of osteonecrosis of the jawMedsafe.govt.nz
Patients with metastatic breast cancer or multiple myelomaHigher risk of osteonecrosis of the jawMedsafe.govt.nz
patients undergoing invasive dental procedureshigher risk of osteonecrosis of the jaw (ONJ)Synapse.patsnap.com
individuals with preexisting low calcium levelshigher risk of hypocalcemiaSynapse.patsnap.com
individuals who do not consume adequate amounts of calcium and vitamin Dhigher risk of hypocalcemiaSynapse.patsnap.com

Medside aggregates publicly available side-effect information for reference only. It is not medical advice. Always consult a healthcare professional before making decisions about medication.

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