Cefuroxime Side Effects — Compared Across 5 Medical Sources

93 side effects

Side effect	Frequency	MedlinePlus	Mayo Clinic	Drugs.com	WebMD	GoodRx
Nausea	common	nausea	nausea or vomiting	nausea or vomiting	nausea	nausea
Vomiting	—	vomiting	nausea or vomiting	nausea or vomiting	vomiting	vomiting
Diarrhea	common	diarrhea	diarrhea	diarrhea	diarrhea	diarrhea
Rash	common	rash	—	—	skin rash	mild drug rash
Itching	common	itching	itching of the vagina or genital area	itching of the vagina or genital area	itching	itching
Hives	—	hives	hives	hives	hives	—
Difficulty breathing	—	difficulty breathing or swallowing	difficulty with breathing	difficulty with breathing	breathing problems or wheezing	—
Wheezing	—	wheezing	tightness of chest or wheezing	tightness of chest or wheezing	breathing problems or wheezing	—
Swelling of the face	—	swelling of the face, throat, tongue, lips, or eyes	—	—	swelling of the face, lips, mouth, tongue, or throat	—
Watery or bloody stools	—	watery or bloody stools	bloody stools	bloody stools	blood in your stool (poop)	bloody stools
Stomach cramps	—	stomach cramps	stomach pains	stomach pains	stomach cramps	stomach pain
Fever	common	fever	fever	fever	fever	fever
Sore throat	—	sore throat	sore throat	sore throat	sore throat	—
Chills	common	chills	chills	chills	chills	—
Seizures	—	seizures	—	—	seizures	—
Colitis	—	—	colitis	—	—	clostridioides difficile colitis
Phenylketonuria worsening	—	—	phenylketonuria (pku) worsening	—	—	—
General feeling of illness	—	—	general feeling of illness or discomfort	general feeling of illness or discomfort	general ill feeling	—
Headache	—	—	headache	headache	headache	headache
Vaginal itching	—	—	itching of the vagina or genital area	itching of the vagina or genital area	—	—
Pain during sexual intercourse	—	—	pain during sexual intercourse	pain during sexual intercourse	—	—
Rigidity	—	—	rigidity	rigidity	—	—
Sweating	—	—	sweating	sweating	—	—
Vaginal discharge	common	—	thick, white vaginal discharge with no odor or with a mild odor	thick, white vaginal discharge with no odor or with a mild odor	vaginal problems	abnormal vaginal discharge
Black tarry stools	—	—	black, tarry stools	black, tarry stools	—	—
Chest pain	—	—	chest pain	chest pain	chest pain/pressure	—
Cough	uncommon	—	cough	cough	cough	—
Loose stools	—	—	loose stools	loose stools	—	—
Painful urination	—	—	painful or difficult urination	painful or difficult urination	burning while urinating	—
Shortness of breath	uncommon	—	shortness of breath	shortness of breath	difficulty catching your breath	—
Sores or ulcers	—	—	sores, ulcers, or white spots on the lips or in the mouth	sores, ulcers, or white spots on the lips or in the mouth	mouth or throat sores	—
Swollen glands	—	—	swollen glands	swollen glands	swollen lymph nodes	—
Unusual bleeding	—	—	unusual bleeding or bruising	unusual bleeding or bruising	easy bruising or bleeding	increased bleeding risk
Unusual tiredness	—	—	unusual tiredness or weakness	unusual tiredness or weakness	unusual weakness or tiredness	—
Back pain	—	—	back, leg, or stomach pains	back, leg, or stomach pains	back pain	—
Bladder pain	—	—	bladder pain	bladder pain	—	—
Bleeding gums	—	—	bleeding gums	bleeding gums	—	—
Bloody or cloudy urine	—	—	bloody or cloudy urine	bloody or cloudy urine	—	—
Body aches	—	—	body aches or pain	body aches or pain	body aches	—
Burning while urinating	—	—	burning while urinating	burning while urinating	burning while urinating	—
Dark urine	—	—	dark urine	dark urine	dark-colored urine	—
Ear congestion	—	—	ear congestion	ear congestion	—	—
Fast or irregular heartbeat	—	—	fast, pounding, or irregular heartbeat or pulse	fast, pounding, or irregular heartbeat or pulse	fast or abnormal heartbeat	—
Frequent urination	—	—	frequent urge to urinate	frequent urge to urinate	—	—
General body swelling	—	—	general body swelling	general body swelling	—	—
Loss of appetite	—	—	loss of appetite	loss of appetite	loss of appetite	—
Loss of voice	—	—	loss of voice	loss of voice	—	—
Lower back pain	—	—	lower back or side pain	lower back or side pain	—	—
Nasal congestion	—	—	nasal congestion	nasal congestion	nasal congestion	—
Nosebleeds	—	—	nosebleeds	nosebleeds	—	—
Pain around the eyes	—	—	pain or tenderness around the eyes and cheekbones	pain or tenderness around the eyes and cheekbones	—	—
Pale skin	—	—	pale skin	pale skin	pale or yellowish skin	—
Pink or red urine	—	—	pink or red urine	pink or red urine	—	—
Sneezing	—	—	sneezing	sneezing	—	—
Stuffy or runny nose	—	—	stuffy or runny nose	stuffy or runny nose	—	—
Swelling of the joints	—	—	swelling of the joints	swelling of the joints	—	—
Tightness of chest	—	—	tightness of chest or wheezing	tightness of chest or wheezing	—	—
White patches in the mouth	—	—	white patches in the mouth or throat or on the tongue	white patches in the mouth or throat or on the tongue	white patches in the mouth or throat or on the tongue	—
Yellowing of the eyes or skin	—	—	yellowing of the eyes or skin	yellowing of the eyes or skin	jaundice	jaundice
Blistering	—	—	blistering	blistering	—	—
Coughing up blood	—	—	coughing up blood	coughing up blood	—	—
Decrease in urine output	—	—	decrease in urine output	decrease in urine output	reduced need to pee	—
Discomfort	—	—	discomfort	feeling of discomfort	—	—
High fever	—	—	high fever	high fever	—	—
Increased menstrual flow	—	—	—	increased menstrual flow	—	—
Joint pain	—	—	joint pain	joint pain	joint pain	—
Liver damage	common	—	—	—	liver damage	elevated liver enzymes
Muscle pain	—	—	muscle pain	muscle pain	—	—
Jaundice	—	—	—	—	jaundice	jaundice
Kidney damage	—	—	—	—	kidney damage	—
Reduced urination	—	—	—	—	reduced need to pee	—
Swelling in the feet or legs	—	—	—	—	swelling in your feet, ankles, or legs	—
Confusion	—	—	—	—	confusion	—
Blood disorders	—	—	—	—	blood disorders	—
Easy bruising	—	—	—	—	easy bruising or bleeding	—
Frequent infection	—	—	—	—	frequent infection	—
Mouth or throat sores	—	—	—	—	mouth or throat sores	—
Muscle twitching	—	—	—	—	muscle twitching, jerking, spasms, tremors, or other uncontrolled movements	—
Stiffening of the arms or legs	—	—	—	—	stiffening of your arms and legs	—
Anxiety	—	—	—	—	feeling anxious, nervous, confused, or a sense of dread	—
Dizziness	—	—	—	—	dizziness, lightheadedness, or feeling like you are about to pass out	—
Falling or loss of consciousness	—	—	—	—	falling or losing consciousness	—
Fast or abnormal heartbeat	—	—	—	—	fast or abnormal heartbeat	—
Anaphylaxis	less common	—	—	—	anaphylaxis	anaphylaxis
Clostridioides difficile diarrhea	rare	—	—	—	antibiotic-associated diarrhea	clostridioides difficile diarrhea
Elevated liver enzymes	common	—	—	—	—	elevated liver enzymes
Vaginal yeast infection	common	—	—	—	vaginal yeast infections	vaginal yeast infection
Abnormal vaginal discharge	common	—	—	—	—	abnormal vaginal discharge
Irritation	common	—	—	—	—	irritation
Clay-colored stool	—	—	—	—	light-colored poop	clay-colored stool
Mild drug rash	common	—	—	—	—	mild drug rash
Severe skin reactions	—	—	—	—	—	severe skin reactions
Allergic reactions	—	—	allergic reactions	allergic reactions	allergic reactions	allergic reactions

4 additional sourcesdidn't return structured side-effect data: My.clevelandclinic.org, Buzzrx.com, Go.drugbank.com, Medfinder.com.

Demographic risk groups

Group	Risk	Sources
pregnant	decreases the effectiveness of some oral contraceptives	MedlinePlus, WebMD
breast-feeding	unknown	MedlinePlus
phenylketonuria (PKU)	contains aspartame that forms phenylalanine	MedlinePlus
children	safety and efficacy have not been established	MedlinePlus, Mayo Clinic, WebMD
diabetic	interference with urine sugar tests	MedlinePlus
breastfeeding	passes into breast milk	Mayo Clinic, WebMD
Patients with kidney disease	Increased effects	Mayo Clinic
Patients with Phenylketonuria (PKU)	Worsening of condition	Mayo Clinic
Patients with colitis or severe diarrhea history	Worsening of condition	Mayo Clinic
child	diarrhea	Drugs.com
Patients with renal dysfunction	Seizures	Drugs.com
Patients with history of delayed hypersensitivity to penicillin	Delayed hypersensitivity reaction	Drugs.com
90-year-old man	Kounis syndrome type I variant	Drugs.com
kidney problems	interaction	WebMD
people with longer treatment	higher risk of vaginal infection	GoodRx
elderly	higher risk of drug-induced liver disease	GoodRx
patients with penicillin allergy	slightly higher chance of allergy to cefuroxime	GoodRx