144 side effects

Side effect	Frequency	PubMed Central	MedlinePlus	RxList	Mayo Clinic	Drugs.com
Nausea	common	nausea	nausea	Nausea	nausea	nausea
Vomiting	—	vomiting	vomiting	—	vomiting	vomiting
Photophobia	—	photophobia	—	—	—	—
Phonophobia	—	phonophobia	—	—	—	—
Drowsiness	—	drowsiness	drowsiness	Drowsiness	drowsiness	—
Dizziness	—	—	dizziness	Dizziness	dizziness	—
Flushing	—	—	flushing	Flushing	flushing or redness of the skin, especially on the face and neck	—
Tingling	—	—	tingling feeling	Tingling	tingling	—
Tiredness	—	—	tiredness	Fatigue	—	—
Weakness	—	—	weakness	Weakness	weakness of the arms and legs	—
Upset stomach	—	—	upset stomach	—	abdominal or stomach pain	upset stomach
Diarrhea	—	—	diarrhea	Diarrhea	—	—
Muscle cramps	—	—	muscle cramps	—	muscle cramps and stiffness	—
Chest pain	—	—	pain, tightness, pressure, or heaviness in the chest, throat, neck, and/or jaw	Throat and chest tightness	chest pain or tightness	—
Shortness of breath	—	—	shortness of breath	—	trouble breathing	—
Fast heartbeat	—	—	fast, pounding, or irregular heartbeat	fast heart rate	fast, slow, irregular, pounding, or racing heartbeat or pulse	—
Bloody diarrhea	—	—	bloody diarrhea	—	—	—
Sudden stomach pain	—	—	sudden or severe stomach pain	—	severe stomach pain	—
Sudden weight loss	—	—	sudden weight loss	—	—	—
Paleness	—	—	paleness or blue color of the fingers and toes	—	—	—
Difficulty breathing	—	—	difficulty breathing or swallowing	—	trouble breathing	difficulty breathing
Rash	—	—	rash, hives	—	skin rash, hives, or itching	hives
Hives	—	—	rash, hives	—	skin rash, hives, or itching	hives
Vision changes	—	—	change in vision	Visual changes	changes in vision	—
Seizures	—	—	seizures	—	—	—
Depression	—	—	—	Depression	—	depressed mood
Insomnia	—	—	—	Insomnia	—	sleep problems
Low blood pressure	—	—	—	Low blood pressure	—	—
Constipation	—	—	—	Constipation	—	—
Dry mouth	—	—	—	Dry mouth	—	—
Sedation	—	—	—	Sedation	—	—
Decreased libido	—	—	—	Decreased libido	—	—
Weight gain	—	—	—	Weight gain	—	—
Weight loss	—	—	—	Weight loss	—	sudden weight loss
Hair loss	—	—	—	Hair loss	—	—
Ringing in the ears	—	—	—	Ringing in the ears	—	—
Shakiness	—	—	—	Shakiness	—	—
Unsteadiness	—	—	—	Unsteadiness	—	—
Confusion	—	—	confusion	Confusion	confusion	confusion
Difficulty concentrating	—	—	difficulty concentrating	Difficulty concentrating	—	—
Loss of appetite	—	—	—	Loss of appetite	—	loss of appetite
Impotence	—	—	—	Impotence	—	—
Burping	—	—	—	Burping	—	—
Gastrointestinal issues	—	—	—	Gastrointestinal issues	—	—
Pain at injection site	—	—	—	Pain at the injection site	—	—
Serotonin syndrome	—	—	—	serotonin syndrome	—	—
Rapid blood pressure increase	—	—	—	rapid increase in blood pressure	—	—
High blood pressure	—	—	—	high blood pressure	—	high blood pressure
Addiction	—	—	—	addiction	—	—
Hypertonic uterine contractions	—	—	—	hypertonic uterine contractions	—	—
Vasospasms	—	—	—	vasospasms/vasoconstrictions	—	—
Abdominal pain	—	—	—	—	abdominal or stomach pain	abdominal discomfort
Anxiety	common	—	—	—	anxiety	severe anxiety
Blurred vision	—	—	—	—	blurred vision	—
Speech changes	—	—	—	—	changes in patterns and rhythms of speech	—
Chills	common	—	—	—	chills	—
Nightmares	—	—	—	—	nightmares	—
Shivering	—	—	—	—	shivering	—
Sweating	—	—	—	—	sweating	—
Swelling	—	—	—	—	swelling of the fingers, hands, feet, or lower legs	swelling of face, lips, tongue, or throat
Tightness in chest	—	—	—	—	tightness in the chest	—
Trouble breathing	—	—	—	—	trouble breathing	difficulty breathing
Blindness	—	—	—	—	blindness	—
Chest tightness	—	—	—	—	chest tightness or heaviness	—
Flushing of skin	—	—	—	—	flushing or redness of the skin, especially on the face and neck	—
Itching	—	—	—	—	itching, pain, redness, or swelling	—
Lightheadedness	—	—	—	—	lightheadedness, dizziness, or fainting	light-headed feeling
Nerve pain	—	—	—	—	nerve pain	—
Numbness	—	—	—	—	severe numbness, especially on one side of the face or body	—
Severe stomach pain	—	—	—	—	severe stomach pain	severe stomach pain
Trouble speaking	—	—	—	—	trouble speaking or swallowing	—
Twitching	—	—	—	—	twitching	—
Unusual bleeding	—	—	—	—	unusual bleeding or bruising	unusual bleeding
Vomiting blood	—	—	—	—	vomiting of blood or material that looks like coffee grounds	vomiting blood
Weakness in arms or legs	—	—	—	—	weakness of the arms and legs	—
Agitation	—	—	—	—	agitation	agitation
Back pain	—	—	—	—	back, leg, or stomach pains	—
Bleeding gums	—	—	—	—	bleeding gums	—
Changes in vision	—	—	—	—	changes in vision	—
Muscle twitching	—	—	—	—	muscle twitching	—
Pinpoint red spots	—	—	—	—	pinpoint red spots on the skin	—
Poor coordination	—	—	—	—	poor coordination	—
Puffiness	—	—	—	—	puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue	—
Restlessness	—	—	—	—	restlessness	restless
Skin rash	rare	—	—	—	skin rash, hives, or itching	severe skin reaction
Unexplained bleeding	—	—	—	—	unexplained bleeding or bruising	unusual bleeding
Unusually warm skin	—	—	—	—	unusually warm skin	—
Burning	—	—	—	—	burning	—
Crawling	—	—	—	—	crawling	—
Prickling	—	—	—	—	prickling	—
Change in color vision	—	—	—	—	change in color vision	—
Change in hearing	—	—	—	—	change in hearing	—
Heartburn	—	—	—	—	heartburn	heartburn
Increased sensitivity to sunlight	—	—	—	—	increased sensitivity of the eyes to sunlight	—
Joint pain	—	—	—	—	joint pain	—
Muscle aching	—	—	—	—	muscle aching or cramping	—
Dark urine	—	—	—	—	—	dark urine
Yellowing of skin or eyes	—	—	—	—	—	yellowing of skin or eyes
Clay-colored stools	—	—	—	—	—	clay-colored stools
Coughing up blood	—	—	—	—	—	coughing up blood
Severe anxiety	—	—	—	—	—	severe anxiety
Panic	—	—	—	—	—	panic
Easy bruising	—	—	—	—	—	easy bruising
Light-headed feeling	—	—	—	—	—	light-headed feeling
Dehydration symptoms	—	—	—	—	—	dehydration symptoms
High potassium	—	—	—	—	—	high potassium
Liver problems	—	—	—	—	—	liver problems
Depressed mood	—	—	—	—	—	depressed mood
Feeling anxious	—	—	—	—	—	feeling anxious
Restless	—	—	—	—	—	restless
Sleep problems	—	—	—	—	—	sleep problems
Severe skin reaction	rare	—	—	—	—	severe skin reaction
Swelling of face	—	—	—	—	—	—
Dyspepsia	—	—	—	—	—	dyspepsia
Nervousness	—	—	—	—	—	nervousness
Irritability	—	—	—	—	—	irritability
Sleeplessness	—	—	—	—	—	sleeplessness
Palpitations	—	—	—	—	—	palpitations
Liver failure	—	—	—	—	—	liver failure
Hepatotoxicity	—	—	—	—	—	hepatotoxicity
Cholestatic hepatitis	—	—	—	—	—	cholestatic hepatitis
Aminotransferase elevations	—	—	—	—	—	aminotransferase elevations
Epigastric distress	—	—	—	—	—	epigastric distress
Abdominal discomfort	—	—	—	—	—	abdominal discomfort
Hemorrhage	—	—	—	—	—	hemorrhage
Peptic ulcers	—	—	—	—	—	peptic ulcers
Perforation	—	—	—	—	—	perforation
Esophageal ulcerations	—	—	—	—	—	esophageal ulcerations
Gastritis	—	—	—	—	—	gastritis
Anaphylaxis	—	—	—	—	—	anaphylaxis
Hypersensitivity reactions	very common	—	—	—	—	hypersensitivity reactions
Bronchospasm	—	—	—	—	—	bronchospasm
Rhinitis	—	—	—	—	—	rhinitis
Conjunctivitis	—	—	—	—	—	conjunctivitis
Urticaria	—	—	—	—	—	urticaria
Angioedema	—	—	—	—	—	angioedema
Skin reactions	—	—	—	—	—	skin reactions
Stevens-Johnson syndrome	very rare	—	—	—	—	stevens-johnson syndrome
Toxic epidermal necrolysis	very rare	—	—	—	—	toxic epidermal necrolysis
Acute generalized exanthematous pustulosis	very rare	—	—	—	—	acute generalized exanthematous pustulosis
Renal dysfunction	—	—	—	—	—	renal dysfunction
Renal failure	—	—	—	—	—	renal failure
Thrombocytopenia	—	—	—	—	—	thrombocytopenia
Agranulocytosis	—	—	—	—	—	agranulocytosis

Demographic risk groups

Group	Risk	Sources
global population	highly prevalent neurological disorder	PubMed Central
pregnant	precaution	MedlinePlus
breast-feeding	precaution	MedlinePlus
smokers	precaution	MedlinePlus
overweight	precaution	MedlinePlus
high blood pressure	precaution	MedlinePlus
high cholesterol	precaution	MedlinePlus
diabetes	precaution	MedlinePlus
seizures	precaution	MedlinePlus
liver disease	precaution	MedlinePlus
kidney disease	precaution	MedlinePlus
children	Reye's syndrome	MedlinePlus, Drugs.com
women	higher prevalence	RxList
pregnant women	harm to the unborn baby	RxList
child or teenager	serious health issues	Drugs.com
Asthmatics	Hypersensitivity reactions	Drugs.com