Olanzapine Side Effects — Compared Across 6 Medical Sources

This tool aggregates publicly available information for reference only. It is not medical advice. Always consult a healthcare professional before making decisions about medication.

55 side effects

Side effect	Frequency	MedlinePlus	Ncbi.nlm.nih.gov	Mayo Clinic	GoodRx	NHS	Missionconnectionhealthcare.com
Nausea	—	nausea and vomiting	—	Nausea	nausea	—	Nausea
Headache	—	—	—	Headache	headache	—	Headaches
Dizziness	—	dizziness	—	Dizziness	dizziness	Dizziness	—
Drowsiness	common	drowsiness	sedation	Drooling	drowsiness	Feeling sleepy	drowsiness
Constipation	common	constipation	—	Constipation	constipation	Constipation	constipation
Dry mouth	common	dry mouth	—	—	dry mouth	—	dry mouth
Weight gain	common	increased appetite, weight gain	weight gain	Rapid weight gain	weight gain	Weight gain	weight gain
Tremors	—	—	tremors	Trembling or shaking	tremors	Twitching or jerking movements	Tremors
Anxiety	—	restlessness	akathisia	Nervousness	—	—	Anxiety and agitation
Agitation	—	agitation	agitation	—	agitation	—	Anxiety and agitation
Insomnia	—	difficulty falling asleep or staying asleep	—	—	insomnia	—	Insomnia
Restlessness	—	restlessness	akathisia	Restlessness	—	—	restlessness
Blurred vision	—	blurred vision	—	Blurred vision	—	—	—
Seizures	—	seizures	seizures	Seizures	seizures	—	—
Stroke	—	stroke	sudden death due to cardiac causes	—	stroke	stroke	—
Tardive dyskinesia	rare	—	tardive dyskinesia	Tic-like movements	tardive dyskinesia	Tardive dyskinesia	tardive dyskinesia
Neuroleptic malignant syndrome	—	—	neuroleptic malignant syndrome	—	neuroleptic malignant syndrome	Neuroleptic malignant syndrome	—
Diabetes	rare	hyperglycemia	impaired glucose tolerance	—	—	diabetes	diabetes
Hyperglycemia	—	hyperglycemia	—	—	high blood glucose	—	—
Ketoacidosis	—	ketoacidosis	—	—	—	—	—
Rash	common	rash that may occur with fever, swollen glands, or swelling of the face	—	Rash	serious skin rashes	Rash	—
Hives	—	hives, skin redness or peeling, difficulty breathing or swallowing	—	—	—	—	—
Itching	—	—	—	Itching of the vagina or genital area	—	—	—
Shortness of breath	—	shortness of breath	—	Difficult or labored breathing	—	—	—
Fast heartbeat	—	fast or slow heartbeat	tachycardia	Slow, fast, pounding, or irregular heartbeat or pulse	—	—	—
Slow heartbeat	—	fast or slow heartbeat	—	Slow, fast, pounding, or irregular heartbeat or pulse	—	—	—
Fainting	—	fainting	—	—	—	—	—
Extreme thirst	—	extreme thirst	—	—	—	—	—
Frequent urination	—	frequent urination	—	Frequent urge to urinate	—	—	—
Extreme hunger	—	extreme hunger	—	—	—	—	—
Weakness	common	weakness	—	Weakness of the arms and legs	—	—	—
Depression	—	depression	—	—	depression	—	—
Difficulty sleeping	—	difficulty falling asleep or staying asleep	—	Difficulty with sleeping	difficulty sleeping	—	Insomnia
Increased appetite	common	increased appetite, weight gain	hyperphagia	—	increased appetite	—	increased appetite
Pain	—	pain in arms, legs, back, or joints	—	Pain during sexual intercourse	abdominal pain	—	—
Breast enlargement	common	breast enlargement or discharge	—	—	Gynecomastia	—	breast enlargement or discharge
Menstrual irregularities	common	late or missed menstrual periods	—	Menstrual irregularities	menstrual irregularities	—	late or missed periods
Sexual dysfunction	common	decreased sexual ability	—	Pain during sexual intercourse	lower sex drive	—	sexual dysfunction
Involuntary movements	—	unusual movements of your face or body that you cannot control	extrapyramidal symptoms	Involuntary movement disorders	—	Twitching or jerking movements	Involuntary movement disorders
Sedation	—	—	sedation	—	sedative effects	—	Sedative effects
Confusion	—	—	—	—	—	—	—
Hallucinations	—	—	—	—	hallucinations	—	Psychosis
Coma	—	coma	coma	—	—	—	—
Respiratory depression	—	—	respiratory depression	—	—	—	—
Cardiac problems	—	—	cardiorespiratory depression	—	—	Blood clots	—
Blood clots	—	—	—	—	—	Blood clots	—
Infections	—	sore throat, fever, chills, and other signs of infection	infections	—	—	Infections	—
Priapism	—	—	—	—	—	Priapism	—
Anaphylaxis	rare	—	—	—	anaphylaxis	Anaphylaxis	—
Cholesterol problems	—	—	—	—	high cholesterol	Cholesterol problems	—
Gynecomastia	common	—	—	—	Gynecomastia	—	—
Nipple discharge	common	breast enlargement or discharge	—	—	nipple discharge	—	breast enlargement or discharge
Fertility problems	common	—	—	—	fertility problems	—	—
Thoughts of suicide	—	—	—	—	thoughts of suicide	—	—
Drug reaction with eosinophilia and systemic symptoms	—	—	—	—	drug reaction with eosinophilia and systemic symptoms	—	—

2 additional sourcesdidn't return structured side-effect data: My.clevelandclinic.org, Medical News Today.

Demographic risk groups

Group	Risk	Sources
older adults with dementia	increased chance of death	MedlinePlus
teenagers	total treatment program	MedlinePlus
pregnant	call your doctor	MedlinePlus
breastfeeding	call your doctor	MedlinePlus
children	medication access	MedlinePlus
younger population	increased risk of metabolic effects	Ncbi.nlm.nih.gov
obese patients	weight gain	Ncbi.nlm.nih.gov
elderly patients with dementia	increased mortality risk	Ncbi.nlm.nih.gov
patients who are obese	adverse effects of weight gain and metabolic dysfunction	Ncbi.nlm.nih.gov
patients with diabetes mellitus	adverse effects of weight gain and metabolic dysfunction	Ncbi.nlm.nih.gov
patients with schizophrenia	poor compliance with treatment	Ncbi.nlm.nih.gov
patients with poor compliance	hospitalization	Ncbi.nlm.nih.gov
older adults	increased risk of death	GoodRx
Diabetes	monitoring required	GoodRx
people with diabetes	closer monitoring	NHS
people with sickle cell disease	priapism	NHS
obese	higher risk of weight gain	Missionconnectionhealthcare.com
pregnant women	risks to babies	Missionconnectionhealthcare.com
infants	impacted in some ways	Missionconnectionhealthcare.com