Tadalafil Side Effects — Compared Across 6 Medical Sources

This tool aggregates publicly available information for reference only. It is not medical advice. Always consult a healthcare professional before making decisions about medication.

99 side effects

Side effect	Frequency	PubMed Central	FDA	Mayo Clinic	Drugs.com	NHS	GoodRx
Nausea	common	—	—	Nausea	nausea	Feeling sick (nausea)	Nausea
Headache	common	headache	headache	Headache	headache	Headaches	Headache
Dizziness	rare	dizziness	dizziness	Dizziness	dizziness	confusion, drowsiness or dizziness	dizziness
Flushing	common	flushing	flushing	Facial flushing and hot flushes	flushing	Facial flushing and hot flushes	Flushing
Indigestion	common	dyspepsia	indigestion	indigestion, upset, or pain	upset stomach	Indigestion	indigestion
Back pain	common	—	back pain	Back pain	back pain	—	Back pain
Muscle pain	—	myalgia	muscle pain	Muscle aches	muscle pain	Muscle aches	Muscle aches
Prolonged erection	rare	—	prolonged erections	Prolonged or painful erection	prolonged erection	Prolonged or painful erection	prolonged erection
Priapism	rare	—	priapism	—	priapism	—	Priapism
Vision problems	rare	sudden vision loss	abnormal vision	Blurred vision	vision changes	Sudden loss of vision	Vision problems
Hearing loss	rare	—	—	Hearing loss	sudden hearing loss	—	Hearing loss
Chest pain	—	—	—	Chest pain	chest pain	Chest pain	—
Heart attack	—	—	heart attack	—	heart attack symptoms	—	—
Stroke	—	—	stroke	—	—	—	—
Fainting	—	syncopal attack	fainting	Fainting	fainting	—	—
Anxiety	—	anxiety	—	—	—	—	—
Depression	—	depression	—	—	—	—	—
Myalgia	—	myalgia	—	—	—	—	—
Joint pain	—	joint pain (arthralgia)	—	Joint or muscle pain	pain in arms, legs, or back	—	limb pain
Muscle weakness	—	muscle weakness	—	—	—	—	—
Sudden vision loss	rare	sudden vision loss	—	—	sudden vision loss	Sudden loss of vision	—
Dyspepsia	common	dyspepsia	—	—	—	—	—
Nasal congestion	common	nasal congestion	stuffy nose	—	stuffy nose	stuffy nose	stuffy nose
Fear of impending death	common	fear of impending death	—	—	—	—	—
Syncopal attack	—	syncopal attack	—	—	—	—	—
Postorgasmic side effects	—	postorgasmic side effects	—	—	—	—	—
Arm pain	—	—	—	Arm pain	—	—	—
Jaw pain	—	—	—	Jaw pain	—	—	—
Blurred vision	—	—	—	Blurred vision	—	—	—
Chills	common	—	—	Chills	—	—	—
Cold sweats	—	—	—	Cold sweats	—	—	—
Confusion	—	—	—	Confusion	—	confusion, drowsiness or dizziness	—
Fast heartbeat	—	—	—	Fast heartbeat	—	—	—
Hearing impairment	—	—	—	Hearing loss	—	—	—
Increased erection	—	—	—	Increased erection	—	—	—
Nervousness	—	—	—	Nervousness	—	—	—
Pain or discomfort in the arms, jaw, back, or neck	—	—	—	Pain or discomfort in the arms, jaw, back, or neck	—	—	—
Pounding in the ears	—	—	—	Pounding in the ears	—	—	—
Slow heartbeat	—	—	—	Slow heartbeat	—	—	—
Spontaneous penile erection	—	—	—	Spontaneous penile erection	—	—	—
Sweating	—	—	—	Sweating	—	—	—
Unusual tiredness or weakness	—	—	—	Unusual tiredness or weakness	—	—	—
Vomiting	—	—	—	Vomiting	—	—	—
Blindness	—	—	—	Blindness	—	—	—
Blistering, peeling, or loosening of the skin	—	—	—	Blistering, peeling, or loosening of the skin	—	—	—
Cough	—	—	—	Cough	—	—	—
Cracks in the skin	—	—	—	Cracks in the skin	—	—	—
Decrease or change in vision	—	—	—	Decrease or change in vision	—	—	—
Diarrhea	—	—	—	Diarrhea	—	—	Diarrhea
Difficulty with speaking	—	—	—	Difficulty with speaking	—	—	—
Double vision	—	—	—	Double vision	—	—	—
Fast, irregular, pounding, or racing heartbeat or pulse	—	—	—	Fast, irregular, pounding, or racing heartbeat or pulse	—	—	—
Hives or welts, itching, skin rash	—	—	—	Hives or welts, itching, skin rash	hives	—	—
Inability to move the arms, legs, or facial muscles	—	—	—	Inability to move the arms, legs, or facial muscles	—	—	—
Inability to speak	—	—	—	Inability to speak	—	—	—
Loss of heat from the body	—	—	—	Loss of heat from the body	—	—	—
Numbness or tingling of the face, hands, or feet	—	—	—	Numbness or tingling of the face, hands, or feet	—	—	—
Red skin lesions, often with a purple center	—	—	—	Red skin lesions, often with a purple center	—	—	—
Red, irritated eyes	—	—	—	Red, irritated eyes	—	—	—
Red, swollen skin	—	—	—	Red, swollen skin	—	—	—
Redness of the skin	—	—	—	Redness of the skin	—	—	—
Redness or soreness of the eyes	—	—	—	Redness or soreness of the eyes	—	—	—
Scaly skin	—	—	—	Scaly skin	—	—	—
Slow speech	—	—	—	Slow speech	—	—	—
Sores, ulcers, or white spots in the mouth or on the lips	—	—	—	Sores, ulcers, or white spots in the mouth or on the lips	—	—	—
Stomach pain	—	—	—	Stomach pain	—	—	—
Sudden cardiac death	—	—	—	Sudden cardiac death	—	—	—
Swelling of the feet or lower legs	—	—	—	Swelling of the feet or lower legs	—	—	—
Belching	—	—	—	Belching	—	—	—
Heartburn	—	—	heartburn	heartburn	—	Indigestion	Heartburn
Stomach discomfort, upset, or pain	—	—	—	stomach discomfort, upset, or pain	—	—	—
Bloody nose	—	—	—	Bloody nose	—	—	—
Body aches or pain	—	—	—	Body aches or pain	—	—	—
Burning, crawling, itching, numbness, prickling, 'pins and needles', or tingling feelings	uncommon	—	—	Burning, crawling, itching, numbness, prickling, 'pins and needles', or tingling feelings	—	—	—
Burning, dry, or itching eyes	—	—	—	Burning, dry, or itching eyes	—	—	—
Sudden hearing loss	—	—	—	—	sudden hearing loss	—	—
Hives	—	—	—	—	hives	—	—
Difficulty breathing	—	—	—	—	difficulty breathing	breathing difficulties	—
Swelling of face, lips, tongue, or throat	—	—	—	—	swelling of face, lips, tongue, or throat	swollen lips, mouth, throat or tongue	—
Light-headed feeling	—	—	—	—	light-headed feeling	—	—
Painful erection	—	—	—	—	painful erection	—	—
Vision changes	—	—	—	—	vision changes	—	—
Ringing in ears	—	—	—	—	ringing in ears	—	—
Seizure or fit	—	—	—	—	—	Seizure or fit	—
Serious allergic reaction	rare	—	—	—	—	serious allergic reaction	—
Swollen lips, mouth, throat or tongue	—	—	—	—	—	swollen lips, mouth, throat or tongue	—
Breathing difficulties	—	—	—	—	—	breathing difficulties	—
Tight throat	—	—	—	—	—	tight throat	—
Skin discoloration	—	—	—	—	—	skin discoloration	—
Rash	—	—	—	—	—	rash	—
Low blood pressure	common	—	—	—	—	—	Low blood pressure
Cold symptoms	—	—	—	—	—	—	Cold symptoms
Limb pain	—	—	—	—	pain in arms, legs, or back	—	limb pain
Sensitivity to light	common	—	—	—	—	—	sensitivity to light
Blue-tinted vision	common	—	—	—	—	—	blue-tinted vision
Hazy vision	common	—	—	—	—	—	hazy vision
Tinnitus	rare	—	—	—	—	—	tinnitus
Vision issues	rare	—	—	—	—	—	vision issues
Erections that last for more than 4 hours	rare	—	—	—	—	—	erections that last for more than 4 hours

4 additional sourcesdidn't return structured side-effect data: Mskcc.org, Theindependentpharmacy.co.uk, Investor.lilly.com, Hims.com.

Demographic risk groups

Group	Risk	Sources
men	higher rates of adverse events	PubMed Central
susceptible individuals	developing POIS	PubMed Central
patients with recent heart attacks or stroke	higher risk	FDA
patients with heart failure	higher risk	FDA
patients with uncontrolled blood pressure	higher risk	FDA
patients with uncontrolled irregular heart beats	higher risk	FDA
patients with severe liver disease	higher risk	FDA
patients with retinal eye problems	higher risk	FDA
patients with left ventricular outlet obstruction	higher risk	FDA
patients with kidney problems	higher risk	FDA, GoodRx
patients with liver problems	higher risk	FDA, GoodRx
pregnant women	heart failure, stroke, or other medical problems	Drugs.com
breastfeeding women	unknown	Drugs.com
women	not approved for use	Drugs.com
people under 18	not approved for use	Drugs.com
people with liver or kidney disease	increased risk of side effects	Drugs.com
children	serious allergic reaction	Drugs.com, NHS
people with chronic eye issues	higher risk of vision problems	GoodRx
patients with heart problems	higher risk	GoodRx
patients with eye conditions	higher risk	GoodRx